Chondrotoxicity and Toxicokinetics of Sparfloxacin in Juvenile Rats
نویسندگان
چکیده
منابع مشابه
Diminished Ciprofloxacin-Induced Chondrotoxicity by Supplementation of Magnesium and Vitamin E in Immature Rats Running Title Ciprofloxacin-induced Chondrotoxicity
Quinolone-induced chondrotoxicity was demonstrated in juvenile rats and multiple other species. Identical damages can be induced in immature rats by feeding a magnesium-deficient diet. The objective of the present study was to investigate whether in reverse the oral supplementation with magnesium, vitamin E or both can diminish the typical quinoloneinduced arthropathy in juvenile Wistar rats. F...
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15 صفحه اولBupivacaine chondrotoxicity.
Editor—We commend Webb and Ghosh for their editorial reviewing the growing evidence for the chondrotoxicity of intra-articular bupivacaine. We would like to add three further points for your readers’ consideration. First, neither magnesium nor bupivacaine is licensed for intra-articular use, although bupivacaine has a good safety record given by this route. Nevertheless, now patient harm has be...
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ژورنال
عنوان ژورنال: Antimicrobial Agents and Chemotherapy
سال: 1998
ISSN: 0066-4804,1098-6596
DOI: 10.1128/aac.42.6.1470